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Large Guide: Supplies

Active Pharmaceutical Ingredient (API)

ExcipientsInactive ingredients in the compounded preparation

Vials

For final product:

For sterile storage:

  • 100mL glass vials (don’t get pre-sterilized, if that’s all that’s available, you must disassemble them and resterilize them yourself)
  • 20mm butyl rubber stoppers
  • 20mm caps

Tools

  • HEPA air purifier or CR box
  • Autoclave or Instant Pot
  • Oven
  • Laminar flow hood (still air box not allowed!)
  • Magnetic stirrer
  • Vial crimper (20mm) (For 5/10/100mL vials)
  • Vial crimper (13mm) (For 3mL vials)
  • Work surface (marble or stainless steel ideal, no wood. cross check material with compatibility with ingredients)
  • Task light
  • Plastic drop cloth sheeting (to make clean room)
  • Milligram scale
  • Pyrex beakers of appropriate size for mixing
  • Glass stirring rod
  • Oven thermometer
  • Laser thermometer
  • Baking dishes
  • Spray bottle
  • Small bottle brush (for vials 3/5/10 and 100mL)
  • New sponge (for scrubbing)
  • Metal tweezers x3 (I prefer curved)
  • Extra large tupperware (e.g. 50 quarts) to store sterile items in

Disposables

  • 18g sterile luer lock needles
  • 18g sterile luer lock dispensing needles (blunt tip) (optional)
  • 20mL sterile luer lock syringes
  • 50mL sterile luer lock syringes
  • Sterile 0.22μm PTFE or nylon syringe filters (not needed for bottle top filtration tek)
  • 0.45μm PTFE or nylon syringe filters (for pre-filtration) (not needed for bottle top filtration tek)
  • Isopropyl alcohol 70% (IPA) (buy exactly 70%)
  • Disinfecting hand soap
  • Alconox (lab detergent)
  • Aluminum foil
  • Distilled water (3+ gallons/10+ liters)
  • Disinfecting, anti-viral wipes (or spray) such as SciCan Optim1 wipes. Get the good stuff.
  • Paper towels or disposable shop towels
  • Painters tape and maybe also duct tape

Personal Protective Equipment (PPE)

  • KN95 or N95 face masks
  • Latex/nitrile gloves
  • Tyvek suit or similar lab garb with wrist cinch
  • Hair covers (includes facial hair)
  • Shoe covers

Random

  • Broom, Mop, etc to clean in preparation
  • Music
  • Plan all your meals
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