HRT Mom is in Beta! You may encounter minor issues with the site content. Stable release expected Summer or Fall 2025 🍁
Skip to Content
Homebrew GuidesInjectables (Medium)Preliminaries

Medium Scale Guide: Preliminaries

Brew Estradiol or Testosterone

Note: Unlicenced manufactuere of testosterone is illegal in the United States and possibly other juristictions. This guide is only for use in juristictions where its use is allowed, or for use with legal substances.

Warning

This guide creates injectables. This injectable is designed to go into your body, bypassing the wonderful filtration system of your digestive organs. Injectable preparations are inherently more dangerous than topicals or orals. Do not skip steps. Do not skimp on prices. You want to do this, so do it right, the first time.

Please contemplate if you’re capable of doing this process correctly before beginning.

Scale

This guide is designed to create roughly 100mL of your target preparation.

It can do more but it’s stretching the capabilites of the equipment and it takes too long. Consider upgrading to the large guide.

This guide is based off of the work of HRT Cat, but makes some needed changes. Thank you to them for the large amount of research they’ve done on this topic. They seem to have abandonded the project so this guide is advancing forward.

There are a number of other guides on the internet for how to do this. I’ve seen guides from HRT Cafe, Tyger, Lily from Oto, Lena (Ultimate DIY Guide), Noir Labs, and “Anonymous.” The steroids community also has a number of guides available.

Speaking broadly, these guides are all advising dangerous practices, some more than others. I strongly advise reading up on the methodology here and educating yourself about why it is the way it is. I will be citing my sources and explaining as much as I can along the way.

DIY vials are a science, not an art. While there will always be a difference in opinion, I know we can collectively step up our game. Just because people “aren’t getting hurt” by the current state of DIY doesn’t mean it’s adequate. I believe that in some circumstances there could be longterm health consequences to poor technique.

Medium Guide Contents

  • Defining and gathering supplies
  • Building a work area
  • Preparing materilas (sterilizing)
  • Working in a still air box
  • Using bubble point tests to ensure filter integrity
  • Mixing preparation, and filtering into 100mL vials
  • Dispensing into smaller vials
  • Capping
  • Visual exam

Pre-Brew Education

Please read up before beginning this process

  • Learn and practice aseptic technique
  • Learn about PPE
  • Read this whole guide start to finish
  • Make a list of how this guide is different from what you’ve done in the past
  • Explore the items in “Topics” area of the sidebar to improve your knowledge

Science-Mind

When you homebrew you’re doing something that is highly regulated and whose secrets are highly guarded. It’s also pretty dangerous to cook something in your kitchen and then to inject it into your own body. You’ll be best served if you adopt a science mindset as you move forward. Ask as many questions as you can about why things are they way they are. Ask if things are safe or not. Ask why we know if they’re safe or not. Keep this up and never stop.

You should be thrilled to learn that there’s a better way to do something. Treat every failure as a success because your set of knowledge just got broader. Be cautious of people with homebrew knowledge who are highly defensive and who have no data to back up why what they do is “safe.”

Accidental skin contact

Be aware that full PPE should be worn while following this guide, including gloves, masks, hair covers, and a tyvek suit. All people can have their hormone profile interferred with if they make accidental skin contact with what they’re brewing. If you are a person who has hormone cycles, or a person who is on testosterone to suppress those cycles, you may notice that accidendal skin contact is detrimental to that cycle.

You will come into contact with this preparation, and you need to have PPE protecting you.

A lot can go wrong here, I’ve seen it first hand. Protect yourself.

Create a guide summary

Preparing for the day of your brew, you should have a personal summary of this guide written out so you don’t have to refer to a website constantly.

Optional: Read the Large Guide

The large guide is way more detailed and has a bunch of techniques that aren’t listed here. You’ll be able to apply many of them to this guide if you choose to. This guide is more of a “bare minimum” needed to produce approximately 20 vials.

Last updated on